Seed Probiotic Review: Dietitian’s Thoughts


Do you struggle with constipation, bloating, or other digestive issues? In this Seed Probiotic review we’ll explain the health benefits of taking a daily probiotic and our experience with one of the best probiotics available today. Taking a probiotic (or a synbotic) is a good way to support the health of your gut microbiome and your overall digestive health.

Collage of fresh vegetables, fruits, meats and bowl of yogurt with probiotics

What is Your microbiome and Why Worry about it?

A microbiome is a collection of all the microorganisms, microbes, and viruses that live in a given ecosystem, including the human body or part of the body, such as your digestive tract. When talking about the human digestive system, this is called your gut microbiome. Your body’s microbiome is a wonderfully complex system that affects everything from mood to immunity to weight loss.

Taking a daily prebiotic supplement (or synbiotic) is one of the best ways to support your microbiome and overall healthy digestion. We’ll explain more about what a synbiotic is next.

A canister of Seed probiotics with fresh fruits, nuts, and vegetables around it.

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What Is A Synbiotic?

A synbiotic goes above and beyond the average probiotic supplement in that it’s a broad-spectrum formulation of probiotics and prebiotics that’s specially designed to deliver strains to the lower digestive system tract to support a healthy gut which in turn supports overall health. 

In this Seed Probiotic review we’ll highlight the benefits of this unique 2-in-1 clinically studied probiotic + prebiotic, the health benefits of taking a daily synbiotic, and why Seed is different thanks to the science-back prebiotic strains inside, and also its unique capsule-in-capsule design to those strains survive exposure to stomach acid and digestive enzymes throughout the digestion process. Seed’s ViaCap® technology results in 100% deliverability to the colon. While the inner capsule contains all of the precious cargo of the probiotic blend, the outer capsule serves as a barrier to oxygen, moisture, and heat so no refrigeration is required, as it is with other probiotic supplements.  

Canister and packets of Seed probiotics on marble countertop

What Are The Benefits Of Seed Daily Synbiotic?

The benefits are many for such a low-lift activity of taking 2 capsules per day. Here are some of the clinically studied benefits:

  • Digestive HealthDS-01TM Daily Synbiotic supports gastrointestinal health in order to support regularity of bowel movements and ease bloating while reinforcing healthy stool hydration and ease of evacuation.
  • Gut Barrier Integrity – May reinforce healthy tight junctions along the gastrointestinal walls. 
  • Gut Immune Function – Helps promote healthy immune systems responses in the gastrointestinal tract and supports production of short-chain fatty acids which in turn nourish the cells of the large intestine and colon.
  • Cardiovascular Health – Helps maintain cholesterol levels already within the healthy range and helps support healthy recycling of cholesterol and bile within the body.
  • Micronutrient Synthesis – Supports folate production via intestinal synthesis of bioactive forms of folate and may support the synthesis of Vitamin B12.
  • Support Skin Health – Supports dermatological health via the gut-skin axis.

*As with all supplements, these claims have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, treat, or prevent any diseases. 

Seed Dailly Synbiotic: The Science Inside

In collaboration with leading scientists and research partners from around the world, Seed has developed scientifically validated and clinically studied probiotics for adults, children, and adolescents.

DS-01TM Daily Synbiotic is a 24 strain probiotic + prebiotic for adults 18 years of age and older. 

It’s the first to take a “microbe-systems approach” with clinically and scientifically studied strain specific benefits that go beyond digestive health, including cardiovascular and heart health, dermatological health, gut health, gut immune function, gut barrier integrity, and micronutrient synthesis.

Canister of Seed probiotics on counter with glass of water, lemon slices, and probiotic capsules in small bowl.

PDS-08TM Pediatric Daily Synbiotic is formulated with 9 probiotic strains + prebiotics for children ages 3-17. Their convenient sachets make it easy to dose just the right amount. Simply mix the content of the sachet into cold or room temperature soft foods (such as yogurt or applesauce) or a liquid (water, milk, or smoothie). The sachets arrive in a BacTrackTM  container to help you remember the last date of use.

Seed synbiotic is free of allergens including wheat, corn, soy, dairy, eggs, fish, shellfish, sesame, tree nuts, and peanuts plus its vegan, gluten-free, and sugar-free. Each 2 capsule dose contains:

  • 53.6 billion AFU (active fluorescent units) in 24 probiotic strains 
  • Prebiotic sourced from Indian pomegranate
  • No binders and free of preservatives
Canister of Seed probiotics on counter with fresh fruits and vegetables around it

Our Honest Review of Seed Synbiotics

We recommend very few dietary supplements instead taking the stance of ‘diet first, supplements second’ but when it comes to gut health we make taking a probiotic a priority.

After several months of using Seed DS-01TM Daily Synbiotic ourselves, we’ve noticed better digestion, including more regular and easy-to-pass bowel movements without side effects such as intestinal symptoms. We noticed less bloating and more frequent bowel movements within a few days. The verdict is still out with regards to our skin as we all already had pretty clear skin to start with and cardiovascular health benefits take longer to ‘see’ if you can see them at all.

We love the refillable glass jar and the recyclable and compostable packaging material the Seed starter kit and refill pouches arrive in. And bonus points for not needing any refrigeration. We have enough on our minds to not have to worry about returning our probiotics to the fridge. 

We realize that it’s not the cheapest probiotic out there but you get what you pay for with Seed. A high-quality product that’s clinically studied and scientifically validated. If you value your health, for less than the cost of a basic drip coffee from your local coffee shop, you can support better digestion, skin, and heart health.

A glass of water with lemon floating int it, Seed probiotics canister in background.

How To Take Seed Synbiotic

The recommendation is to take 2 capsules a day and an empty stomach with a glass of water. They can be taken first thing in the morning or before bed, whichever is easiest for you and fits into your routine. There’s no need to keep them in the refrigerator because they’re shelf-stable so if keeping them next to your toothbrush in your bathroom helps you remember to treat yourself to that good bacteria, then do what works for you.

Cost: We Break It Down For You

Seed DS-01 Daily Synbiotic costs $49.99 per month or $1.60 per day. Refills come in a 30-day supply that you just add right to your reusable glass jar. Place your first order at and use code REALFOOD for 15% off your first month’s supply of Seed DS-01TM Daily Synbiotic OR Seed PDS-08™ Pediatric Daily Synbiotic.

We love Seed’s focus on sustainability and their commitment to discovering and developing sustainable biomaterials and refill systems. Your first box, or Welcome Kit, includes:

  • Recyclable shipping box made from eco-friendly paper crafted from algae
  • A bio-based tray that is recyclable and home compostable
  • Refillable glass jar that contains your first 30-day supply of DS-01TM
  • Complimentary travel vial to take your probiotics with you when you’re on the go
  • Refills arrive in a pouch made with corn-based materials that are curbside- or home-compostable
Overhead view Seed probiotic canister on counter with capsules scattered around.

Where to Buy Seed Synbiotic

Seed DS-01TM Daily Synbiotic and Seed PDS-08TM Pediatric Daily Synbiotic is available as a monthly subscription via their website Because of their high-quality nature, you won’t find them on discount retail sites or Amazon. Your first order includes a glass jar with a 30-day supply of Seed plus a handy glass travel vial for taking Seed on the go with you plus shipping is free.

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Collage of Seed probiotic canister, bowl of fresh fruit, glass of lemon water, overhead view several fruit, vegetables, and meats on counter.

All opinions in this Seed Probiotic Review are our own. We do receive an affiliate commission if you purchase Seed through our links. Before we were approved as an affiliate, we completed an educational course on the science behind Seed.

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